18+ Kansen 2: Inzai Toshi

Kansen 2 (like the first episode) takes place during the initial outbreak of the Unknown virus epidemic, but the protagonists here have a much harder lot because they are stuck in the middle of a contaminated city immediately after its destruction by a mysterious cataclysm.

Stalked by hordes of infected maniacs, Hiroshi Ookura and his friends seek safety inside a mostly intact shopping mall, but madness and death are everywhere...

(Source: VNDB)